The new vaccine has received approval for the prevention of seasonal influenza in people between the ages of 18 and 49. Flublok is made with a process that does not need the virus to be grown in chicken eggs, as current vaccines are currently made. This means that in case of a pandemic, the vaccine could be ready much earlier.
Large quantities of hemagglutinin (HA), the influenza virus protein, are produced by the Flublok's original manufacturing technology. HA is the active ingredient in all inactivated flu shots that is crucial for entry of the virus into the body's cells.
Most of the antibodies that stop the infection of the influenza virus are targeted against HA. Although the technology is new to flu vaccine production, it is used to make vaccines that have received approval from the FDA to prevent other spreadable illnesses.
Karen Midthun, M.D., director of the FDA's Center for Biologics Evaluation and Research, said:
"This approval represents a technological advance in the manufacturing of an influenza vaccine. The new technology offers the potential for faster start-up of the vaccine manufacturing process in the event of a pandemic, because it is not dependent on an egg supply or on availability of the influenza virus."
In order to recognize strains that may be the source of most sicknesses in the approaching season, the World Health Organization (WHO), the FDA, the CDC, and other public health specialists work together each year to analyze influenza disease surveillance and laboratory data gathered worldwide.
The FDA chooses the various flu strains each year that U.S. manufacturers should include in their vaccines for the upcoming flu season by using the data analyzed, as well as the suggestions made by the FDA's Vaccines and Related Biological Products Advisory Committee.
When the strains in the vaccines match the flu virus strains in circulation, people are much better protected from getting the flu.
Flublok protects againsts two influenza virus A strains, H1N1 and H3N2, and one influenza virus B strain, because it consists of three, full-length recombinant HA proteins.
The vaccine will be assessed each year by the FDA, as it does with all other flu shots, before the public receives it each flu season.
The FDA will evaluate the recombinant HA proteins that are produced in the baculovirus expression system and included in the new vaccine.
Research conducted at different locations in the United States analyzed the effectiveness of Flublok. Approximately 4,600 people participated in the study, half received Flulbok and the other half were given a placebo.
Results showed that Flublok not only protected against the 3 matched strains that were contained in the shot, but was also found to be 44.6% effective against all circulating influenza strains.
The vaccine's safety was assessed in a study consisting of an estimated 2,500 people who received the shot.
The adverse reactions that were reported most frequently included:
Author:Victoria Jackson and Mike Shuttleworth Phone: 970-846-8692 Dated: January 17th 2013 Views: 647 About Victoria Jackson and: The Steamboat Luxury Team -Vicki Jackson and Mike Shuttleworth
Vicki Jackson has been a Realtor f...
About Coldwell Banker Distinctive Properties - The Steamboat Luxury Team
COLDWELL BANKER notables:
NUMBER OF U.S. TRANSACTION SIDES: 727,415
AVERAGE U.S. SALES PRICE: $315,324 (14.2% higher than the NAR 2016 Average**)
TOTAL U.S. SALES VOLUME: $229.4 BILLION
NUMBER OF U.S. $1 MILLION+ TRANSACTION SIDES: 24,790 ($1.9 million average sales price)
INDEPENDENT CONTRACTOR SALES ASSOCIATES/REPRESENTATIVES WORLDWIDE: 88,000+
COLDWELL BANKER OFFICES WORLDWIDE: approximately 3.000
The Steamboat Luxury Team, 10th among all Coldwell Banker Teams in Colorado. from its very formation, has been unique in our approach to real estate, and how we take care of our clients. Our temperament, ethics, experience and success in residential, investment, and commercial real estate separates us from other real estate agents in the valley.. As a result of our approach, all of our associates work together to assist you with every aspect of your real estate transaction. This means that instead of just one agent, you have an entire team of professionals working for you. Local knowledge supported by America’s premier Real Estate Company
Full Time Professionals Premiere GGlobal Luxury Trained Agents in the Valley Highly Skilled Negotiators Tremendous Support Staff Ranked 10 in Colorado among all Coldwell Banker teams. Winner of Coldwell Banker Premier Office Status Winner of Coldwell Banker Presidents Elite Status
""I used Mike and Vicki to handle short sales for me on multiple income properties. They were professional and informative, walking me through the process and making sure everything was done in a timely fashion. I would use them again and recommend them to anyone looking to buy or sell real estate.""